Contact Lens Solution
HealthCare Professionals

References

The following references demonstrate the wettability, comfort, cleaning, and disinfection of OPTI-FREE® RepleniSH® MPDS and OPTI-FREE® EXPRESS® MPDS.

Lens Wettability

  1. Meadows DL, Ketelson HA, McQueen N, Stone R. Dynamic Wetting Behavior of pHEMA-MAA and Silicone Hydrogel Contact Lenses. Invest. Ophthalmol. Vis. Sci. 2004 45:E-Abstract 1553.
  2. Ketelson HA, Meadows DL. Wettability of Soft Contact Lenses: New Thoughts About an Old Problem. Review of Contact Lenses, October 2004; 34-38.
  3. Ketelson HA, Meadows DL, McQueen N, Stone RP. Enhancing Wettability with Multi-purpose solutions. Review of Cornea & Contact Lenses, January/February 2005: 44-47.
  4. Ketelson H, Meadows D, McQueen N, Stone R. Wettability of Silicone Hydrogel Lenses in the Presence of Tear Components. Review of Cornea & Contact Lenses, April 2005; 24-28.
  5. Meadows DM, Ketelson HA, McQueen N, Stone R. The Effect of Tear Components on the in vitro Wettability of Silicone Hydrogels. Invest. Ophthalmol. Vis. Sci. 2005. 46: E-Abstract 906.
  6. McQueen N, Ketelson HA, Meadows DL, Stone R. The Influence of Surfactants and Bulk Water on the Wettability of Contact Lenses. Poster presented at AOA, August 2005.
  7. Ketelson HA, Meadows DL, Stone RP. Dynamic Wettability Properties of a Soft Contact Lens Hydrogel. Colloids and Surfaces B: Biointerfaces 40(2005) 1-9.

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Comfort

  1. Larsen S, Smith C, Mathis J, Smith PB, Bronner C, Maynard R, Fontana F, Ghormley R. Comfort differences between multi-purpose solutions. Reprinted from Contact Lens Spectrum, December 2002.
  2. Pritchard N, Fonn D, Brazeau D. Discontinuation of contact lens wear: a survey. ICLC, Vol. 26, 1999.
  3. Epstein A. Contact Lens Dropout. Review of Contact Lenses, July 2003, 28-31.
  4. Stiegemeier MJ, Cedrone R, Evans D, Friederich G, Holle D, Jenkins W, Lutzi D, Roberson R, Schenker H, White E, Zigler L. Clinical performance of "no rub" multi-purpose solutions. Poster presented at BCLA 2001.
  5. Potter B, Stiegemeier M, Wilson M, Larsen, Friederichs G. A Clinical Evaluation of Solutions. Review of Cornea & Contact Lenses, November 2005.
  6. Stiegemeier M, Friederichs G, Hughes J, Larsen S, Movic W, Potter W. Clinical evaluation of a new multi-purpose disinfecting solution in symptomatic contact lens wearers. Contact Lens & Anterior Eye, May 2006.
  7. Kern J, Napier L, Meadows, D. Assessment of patient satisfaction with a new multi-purpose disinfecting solution using a patient outcome survey. Alcon Laboratories, Inc. Poster presented at: AOA June 2007; Boston, Mass.

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Cleaning

  1. Guillon M, Maissa C. Clinical acceptance of two multi-purpose solutions containing HPMC versus citrate-based MPS without rubbing. The CLAO Journal, October 2002, Vol. 28, 4:186-191.
  2. Christensen M, Keith D, Stone R, Stein J. How lens care products stack up. Review of Contact Lenses, May 2002.
  3. Hong B, Stauffer P, Meadows D, Keith D. Assessment of Cleaning Efficacy of Contact Lens Multi-Purpose Disinfecting Solution. Invest. Ophthalmol Vis. Sci. 2005. 46:E-Abstract 914.

Disinfection

  1. Lebow, Kenneth A, Beach V. Are all multi-purpose contact lens solutions created equal? Optometric Management, October 2002.
  2. Rosenthal RA, Henry CL, Buck SL, Bell WM, Stone RP, Schlech BA. Extreme testing of contact lens disinfecting products. Reprinted from Contact Lens Spectrum, July 2002.
  3. Rosenthal RA, Bell WM, Schlech BA. Evaluation of a new contact lens disinfection formulation for disinfectant efficacy. Poster presented at AOA 2005.
  4. Rosenthal RA, McAnally CL, Dassanayke N, Schlitzer RL, Schlech BA, Meadows DL. TheE Effect of Storing Lenses on the Antimicrobial Activity of Multipurpose Solutions for Contact Lenses. Invest. Ophthalmol. Vis. Sci. 2007. 48:E-Abstract 5398.

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Corneal Response to Multi-Purpose Solutions

  1. Jones L, Jones D, Houlford M. Clinical Comparison of Three polyhexanide-preserved disinfecting solutions. Contact Lens Ant. Eye, 1997;20(1) 23-30.
  2. Caroline P, Campbell R. Multipurpose Non-Keratitis. Contact Lens Spectrum, March 1997.
  3. Young G, Pritchard N, Hunt C, Coleman S. Evaluation of Corneal Staining Related to Multipurpose Disinfecting Systems. Poster presented at BCLA, 2001.
  4. Garofalo RJ, Dassanayake N, Carey C, Stein J, Stone R, David R. Corneal Response of Chemical Agents Released by Hydrogel and Silicone-Hydrogel Lenses as a Function of Time. Invest. Ophthalmol. Vis. Sci. 2004. 45:E-Abstract 1538.
  5. Lebow K, Schachet J. Evaluation of corneal staining and patient preference with use of three multi-purpose solutions and two brands of soft contact lenses. Eye & Contact Lens, Vol. 29, No. 4, October 2003.
  6. Pritchard N, Young G, Coleman S, Hunt C. Subjective and objective measures of corneal staining related to multi-purpose care systems. Contact Lens & Anterior Eye 26:2003;3-9.
  7. Stiegemeier MJ, Cedrone R, Evans D, et al. Clinical Performance of 'no rub' Multi-Purpose Solutions. Contact Lens Ant. Eye, 2004;27:65-74.
  8. Jones L, Dumbleton K, Bayer S, et al. Clinical performance and corneal staining associated with silicone hydrogel materials used on a daily wear basis. Presentation to AAO meeting, Hawaii, May 2004.
  9. Jones L, MacDougall N, Sorbara GL. Asymptomatic corneal staining associated with the use of balafilcon silicone-hydrogel contact lenses disinfected with a polyaminopropyl biguanide-preserved care regimen. Optcom Vis Sci. 2002;79:753-761.
  10. Garofalo R, Dassanayake N, Carey C, et al. Corneal staining and subjective symptoms with multi-purpose solutions as a function of time. Eye & Contact Lens, 2005; 31: 166-167.
  11. Dassanayake N, Garofalo R, et al. Correlating biocide uptake and release profiles with corneal staining and subjective symptoms. Poster presented at ARVO, 2005.
  12. Jones L, Keir N, et al. The impact of post-insertion time on corneal staining and comfort with group II hydrogel materials disinfected with various lens care regimens. Poster presented at ARVO, 2005.
  13. Vehige JG, Simmons PA, Anger C, Graham R, Tran L, Brady N. Cytoprotective properties of carboxymethylcellulose (CMC) when used prior to wearing contact lenses treated with cationic disinfecting agents. Eye & Contact Lens, Vol. 29, No. 3 (2003) pp. 177-180.
  14. Townsend W, Katims S, Rosen J. Investigating a New-generation Multi-purpose Solution. Contact Lens Spectrum, December 2005.
  15. Jalbert I, Carnt N, et.al. Solution Toxicity in Soft Contact Lens Daily Wear. Poster presented at ARVO, 2006.
  16. Andrasko GJ, Ryen KA, Garofalo RJ, Lemp JM. Octular Response Observed with Silicone Hydrogel Lenses and Multi-Purpose Solution Combinations. Poster presented at AOA, June 2006.
  17. Andrasko GJ, Ryen KA, Garofalo RJ, Lemp JM. Compatibility of silicone hydrogel lenses with multi-purpose solutions. Invest Ophthalmol Vis Sci. 2006; 47:ARVO E-Abstract 2392.
  18. Carnt N, Jalbert I, Stretton S. Naduvilath T, Papas E. Solution toxicity in soft contact lens daily wear is associated with corneal inflammation. Optom Vis Sci. 2007;84:309-315.
  19. Fleiszig S. The pathogenesis of contact lens-related keratitis. Optom Vis Sci. 2006;83:866-873.
  20. Hall JQ, Paugh JR, Peinovich MC, Ramsey AC, Meadows D. A pilot study of the effect of silicone-hydrogel lenses and marketed multipurpose solutions on human epithelial barrier function. Invest Ophthalmol Vis Sci. 2007; 48:ARVO E-Abstract 5400.
  21. Paugh JR, Webb JR, Ramsey AC, Meadows D, Napier L. Clinical and epithelial barrier evidence of lens material and multipurpose solution bio-incompatibilities. Poster presented at BCLA; May 2008; Birmingham, UK.
  22. Schachet J, Zigler L, et al. Clinical assessment of a new multi-purpose disinfecting solution in asymptomatic and symptomatic patients. Poster presented at: AAO; December 2006; Denver, CO.

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Additional Supporting Data

  1. Tripathi, Brenda J, et al. Hydrogen peroxide damage to human corneal epithelial cells in vitro, implications for contact lens disinfection systems. Arch. Ophthalmology, 1989, Vol. 107.
  2. Chin TL, Abelson MB, Shapiro A. Comparison of comfort: multi-purpose contact lens solutions. Review of Contact Lenses, November 2002: 1-3.
  3. Løfstrøm T, Kruse A. Multi-purpose contact lens solution-an overlooked risk factor? CLAO 2001.
  4. Fonn D. Preventing contact lens dropouts. Contact Lens Spectrum, 2002;17:26-32.